Preclinical Production

Veliter’s VPS™ （Veliter Preclinical Service）provides affordable, quality oligonucleotides with fast turnaround times. Our team specializes in small batch sizes at μmol- to mmol-scales, from 50 mg to 10’s of grams of oligonucleotides for research and early pre-clinical applications to facilitate your program successful.

A comprehensive solution

Veliter’s VPS™ offers custom oligonucleotide manufacture for non-cGMP applications. All oligonucleotides are synthesized, purified, desalted and freeze dried using best-view platform processes pre-tailored for large scale manufacturing. Products are analyzed in house using phase-appropriate analytical methods. Our team can handle a wide array of chemistries and sequence.

Complex chemistry challenging

Our scientists have the experience to bring you the most challenging chemistry in oligo synthesis. We can perform all types of conjugation reactions, including conjugation to various PEG, GalNAc and analogues regardless of off/on column. We routinely make longmers and CRISPR sequences (Aptamer and sgRNA). We can even make sequences using your proprietary amidites if necessary to facilitate your preclinical development trials.

Minimize risk from the beginning

Veliter VPS service can offer preclinical oligonucleotide with Veliter’s platform quality and expertise. Building oligo knowledge with Veliter from the beginning can minimize the risks and expenses incurred as projects progress such as tech transfers cost, process surprises, and absolutely extensive development time. We can take your project from mgs of preclinical material to hundreds of kilograms of commercial supply.

Project management from end to end

Veliter’s experienced technical team will evaluate the most appropriate methods for your sequence’s chemistry from the start to end, and our project managers are available to answer questions and keep you updated on the status of your project and keep in touch even post-project.

Positive oligo program experience, from end to end

Focusing on your needs and building long-term partnerships, your own Veliter’s project manager will be flexible and responsive. This is Veliter’s approach to make your oligonucleotide program move smoothly through pre-clinical to commercial.