Oligonucleotide drug discovery

Our oligonucleotide drug discovery platform is equipped with experienced scientists and state-of-the-art facilities to support your discovery synthesis of oligonucleotides, complex conjugates, monomers, ligands and linkers, from sequence design to Pre-Clinical Candidate (PCC).

Our Services

We provide custom synthesis from nmol to mmol. Our services cover all types of oligonucleotides with dedicated analytical support for all required testing.

We support all types of oligonucleotides, including but not limited to:

DNA, Primer, Aptamer
RNA, miRNA, shRNA, saRNA
siRNA
sgRNA
ASO, PMO

Experience Highlight

VPS^TM platform, high-efficiency delivery service, and fast delivery in one week
A variety of complex modification sequence synthesis ability, such as LNA, PS/PN replacement of PO, circular siRNA/ASO, etc
Extremely efficient single-step coupling efficiency, average single-step coupling efficiency >99%
100+oligonucleotides per month
20+ challenging modified oligonucleotide synthesis
Abundant nucleic acid monomer, GalNAc reserve
high throughput synthesizer (192 channels, 48 channels, 16 channels)

Broad Purification Capability

IP-RP HPLC: Milligram scale purification with endotoxin control
Anion-Exchange Chromatography (AEX): From gram scale to large scale purification
Customized Purification Method: Method development by combining IP-RP HPLC and AEX HPLC for high purity requirement

Positive oligo program experience, from end to end

Focusing on your needs and building long-term partnerships, your own Veliter’s project manager will be flexible and responsive. This is Veliter’s approach to make your oligonucleotide program move smoothly through pre-clinical to commercial.