Synthetic Engineer

Location: Dongguan, China

Full-Time

Responsibilities:

  1. Conduct oligonucleotide synthesis process development according to project requirements, design synthesis routes, carry out synthesis experiments, and continuously optimize reaction conditions.
  2. Responsible for organizing and archiving experimental records and writing purification process SOPs.
  3. Responsible for the initiation research of new product development and secondary development of existing products.
  4. Collect quality and process-related information, identify factors affecting product quality, initiate research projects, and continuously improve product quality.
  5. Develop specific research and implementation plans for product process improvement, and organize experimental research on process improvement.
  6. Provide technical guidance for the implementation of product process improvements, analyze and solve problems encountered in the new process commissioning process.
  7. Responsible for trial production and production of new products, participate in the acceptance of new product processes, and adjust and improve various technical indicators of new product production processes.
  8. Conduct research on improving the quality standards and testing methods of existing products to ensure continuous improvement of product quality.
  9. Complete other tasks assigned by superiors.

Requirements:

  1. Master’s degree or above in organic chemistry, applied chemistry, chemical engineering, or biochemistry-related fields.
  2. Experience in organic synthesis process development or production of peptides or oligonucleotides is preferred.
  3. Familiarity with operation and maintenance of AKTA Oligopilot Plus, Oligopilot, AKTA Explorer, AKTA Process, and preparative HPLC is preferred.
  4. Familiar with various chromatography techniques and fillers (ion exchange, reverse phase, SEC, etc.).
  5. Familiarity with ultrafiltration and diafiltration techniques is preferred.
  6. Fluent in spoken and written English, proficient in reading professional English literature.
  7. Detail-oriented, proactive, able to withstand significant work pressure, and have strong teamwork skills.
  8. Salary negotiable based on capabilities.